Phenolic Hydroxyl Ionization in Pepsinogen

Phenolic hydroxyl ionization in papain.

Various properties of crystalline papain have been under investigation in this laboratory for several years in attempts to understand the specificity, mode of action, and other aspects of the behavior of this enzyme (1). Inasmuch as papain must be in its native state to retain its enzymic activity, a knowledge of the role of the amino acid side chains in maintaining conformation is essential. T...

Nanoscale hydroxyl radical generation from multiphoton ionization of tryptophan.

Exposure of solutions containing both tryptophan and hydrogen peroxide to a pulsed ( approximately 180 fs) laser beam at 750 nm induces luminescence characteristic of 5-hydroxytryptophan. The results indicate that 3-photon excitation of tryptophan results in photoionization within the focal volume of the laser beam. The resulting hydrated electron is scavenged by hydrogen peroxide to produce th...

Pepsinogen BASIL

Estimation of serum pepsinogen.

Unusual method for phenolic hydroxyl bridged lanthanide CPs: syntheses, characterization, one and two photon luminescence.

A "basophilic method" for phenolic hydroxyl bridged lanthanide coordination polymers (CPs) was developed. With this method, eleven CPs with the general formula of [Ln(HL1)L1·H(2)O](n) (Ln = Tb (1), Nd (2), Eu (3), Gd (4), La (5), Er (6), Y (7), H(2)L1 = 4-methyl salicylic acid) and [Ln(HL2)L2·2MeOH](n) (Ln = Eu (8), Tb (9), Gd (10), La (11), H(2)L2 = 3-hydroxy-2-naphthoic acid) were synthesized...